| ORIGINAL ARTICLES |
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| Year : 2023 | Volume
: 8
| Issue : 1 | Page : 30-33 |
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Relationship between serum IgE level and childhood nephrotic syndrome with atypical presentation
Munmun Chowdhury1, Pranab K Chowdhury1, Mohammed Maruf-Ul Quader2, Muhammad Jabed Bin Amin Chowdhury1, Zabeen Choudhury1, Susmita Biswas2
1 Department of Pediatrics, Chittagong Medical College Hospital, Chattogram, Bangladesh
2 Department of Pediatric Nephrology, Chittagong Medical College Hospital, Chattogram, Bangladesh
Correspondence Address:
Dr. Munmun Chowdhury
Research Assistant, Department of Pediatrics, Chittagong Medical College Hospital, Chattogram 4203
Bangladesh
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/pnjb.pnjb_27_22
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Background: Patients with nephrotic syndrome (NS) have altered serum immunoglobulin E (IgE) levels during relapse and remission, while presentation may be typical or atypical. Objective: To evaluate serum IgE level in childhood NS with the atypical and typical presentation. Materials and Methods: A total of 66 children with NS aged between 1 and 12 years were enrolled in this cross-sectional study. Among them, 33 children were with atypical presentations, and an equal number of children were with the typical presentations. Serum IgE level was measured in all cases. Result: The mean age of patients was 5.9 ± 3.1 years with a male-to-female ratio of 1.4:1. The mean serum IgE level was 1063.2 ± 1042.6 IU/mL in NS atypical presentation and 1099.8 ± 842.1 IU/mL in NS typical presentation, both of which were higher than the normal range for age but statistically not significant (P = 0.877). Conclusion: Elevated level of serum IgE is a feature of childhood NS with atypical and typical presentations. |
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