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Year : 2022  |  Volume : 7  |  Issue : 2  |  Page : 63-66

Concomitant infection of typhoid and rickettsia with dengue fever in acute febrile patient

Department of Pediatrics, Kurmitola General Hospital, Dhaka Cantonment, Dhaka, Bangladesh

Correspondence Address:
Dr. Ferdousi Hasnat
Department of Pediatrics, Kurmitola General Hospital, Dhaka Cantonment, Dhaka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/pnjb.pnjb_5_22

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Rationale of the study and objectives: Dengue fever is one of the major causes of acute febrile illness. Other causes of febrile illness may be associated with dengue. This cross-sectional observational study was done to find out other coinfections such as typhoid, malaria, and rickettsia with dengue in an acute febrile patient and aimed to reduce the morbidity and mortality of patients. Materials and Methods: This study was conducted at Kurmitola General Hospital from June 2019 to November 2019. A total of 244 patients were included in this study. All patients were admitted to the hospital with fever. All investigations that aimed to diagnose the acute febrile illness were done. Results: Among 244 patients, 62.29% patients were tested positive for dengue, 26.22% for rickettsia, and 11.47% for typhoid. Dengue monoinfection was 44.26%, and coinfection was 18.03%. Malarial case was not found. The mean age of children was 6.4 years. Majority (75%) came from rural areas, and 64.75% of studied children were male. Fever, myalgia, arthralgia, and gastrointestinal symptoms such as abdominal pain, vomiting, loose motion were the main symptoms, and jaundice, hepatomegaly, and splenomegaly were the main signs both in monoinfection and coinfection. Leukopenia, thrombocytopenia, raised serum alanine transaminase, and elevated hematocrit were found in monoinfection as well as in coinfection. Conclusion: Symptoms of monoinfection and coinfection were overlapping, but treatment was rather different and difficult. So for proper treatment, early detection was necessary for reducing death rate and complication in acute febrile illness.

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